- More common in women 40-60 years old
- Genetics, remissions and exacerbations
- Fingers, hands, wrists, knees, feet
- Rheumatoid Factor – antibody that reacts with fragments of IgG
Signs and Symptoms
- Fatigue
- Anorexia
- Weight loss
- Crepitus
- Morning stiffness
- Increased ESR
- Pain
- Malaise
- Fever
- Increased capillary permeability
