Monday, July 30, 2012

Pathophysiology - Spontaneous Abortion

SPONTANEOUS ABORTION
  • Is the unintended termination of pregnancy at any time before the fetus has attained viability (20 weeks gestation or fetal weight of <500g)
  • Cause frequently unknown, but 50% are due to chromosomal abnormalities
  • Exposure or contact with teratogenic agents
  • Poor maternal nutritional status
  • Maternal agents with virus such as rubella, cytomegalovirus, active herpes, and toxoplasmosis, or specific bacterial microorganisms that put the pregnancy at risk
  • History of diabetes, thyroid disease, anticardiolipin antibodies, or lupus erythematosus
  • Smoking or drug abuse of both
  • Immunologic factor by which the mother and father are genetically similar, with major antigens that cause the maternal immune system to reject the embryo
  • Abnormal uterine development or structural defect in the maternal reproductive system (including an incompetent cervix)
  • Environmental factors such as drugs, radiation, or trauma
CLINICAL MANIFESTATIONS
  • Uterine cramping
  • Low back pain
  • Vaginal bleeding usually begins as dark spotting, then progresses to frank bleeding as the embryo separates from the uterus
  • B-hCG levels may be elevated for as long as two weeks after loss of the embryo

DIAGNOSTIC EVALUATION
  • Ultrasound evaluation of the gestational sac or embryo
  • Visualization of the cervix, presence of dilation or tissue evaluated
COMPLICATIONS
  • Hemorrhage
  • Uterine infection
  • Septicemia
  • Disseminated intravascular coagulation (DIC) in a missed abortion
NURSING ASSESSMENT
  1. Evaluate the amount of and color of blood that is present: determine the time the bleeding began and any precipitating factors.
  2. Determine whether a positive pregnancy test has previously been obtained, also the date of the last menstrual period.
  3. Monitor vital signs for indication of complications such as haemorrhage, infection
  4. Evaluate any blood or clot tissue for the presence of fetal membranes, placenta or fetus
NURSING DIAGNOSES
  1. Risk for fluid volume deficit related to maternal bleeding
  2. Anticipatory grieving related to loss of pregnancy, cause of the abortion, future childbearing
  3. Risk for infection related to dilated cervix and open uterine vessel
  4. Pain related to uterine cramping
NURSING INTERVENTIONS
  1. Maintaining fluid volume
  2. Providing support through the grieving process
  3. Preventing infection
  4. Promoting comfort

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